Korean J Nephrol.
2000 Nov;19(6):1086-1090.
Study for the Lack of Mental Changes to Severe Hyperglycemia in Diabetic Patients with Renal Failure
- Affiliations
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- 1Department of Internal Medicine, Hanyang University Kuri Hospital, Korea.
- 2Department of Internal Medicine, Chonbuk National University, Korea.
- 3Department of Internal Medicine, Kyunghee University, Korea.
Abstract
- In diabetic patients who were being treated with hemodialysis, coma and other neurological deficits did not occur in spite of extremely elevated serum glucose levels. In this report, we compared diabetic patients with renal failure in severe hyperglycemia with nonketotic hyperosmolar coma patients with normal renal function to know what affect mental changes. Mental changes were not present in diabetic patients with renal failure. These patients with renal failure showed more severe hyperglycemia, but corrected serum sodium concentration and calculated effective serum osmolality were low. So it is suggested that corrected serum sodium concentration and effective serum osmolality are more important factor affecting mental changes than high blood glucose levels in diabetic patients with renal failure, due to absence of osmotic diuresis.
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