Korean J Nephrol.  2002 Nov;21(6):924-931.

The Clinical Outcome and Related Factors of ARF in Survived Patients after CPR

• Kim HJ
• Song JH
• Lee SW
• Lee JH
• Kwak YG
• Kim ES
• Kim HS
• Lim HJ
• Kim MJ

Abstract

BACKGROUND: The purpose of the study was to evaluate the prevalence, related factors, and outcome of acute renal failure (ARF) developed in the patients who survived following a cardiac arrest.
METHODS
A retrospective analysis of medical records was underwent in 24 patients who survived among 68 patients receiving cardiopulmonary resuscitation (CPR) at the emergency center of Inha-hospital, Sungnam, Korea, from January 1999 to February 2001. Clinical factors before, during and after CPR were compared and contrasted between the patients who manifested ARF after CPR and those who did not.
RESULTS
ARF occurs at 33% following CPR. ARF group showed high baseline creatine kinase (CK) level, longer duration of resuscitation, and larger dosages of epinephrine usage during CPR. During 24 hours after CPR, mean arterial pressure and hourly urine output were significantly lower and dopamine was administered significantly higher in ARF group. Among them seven patients died in 2.3+/-0.8 hospital day with a mean serum creatinine of 2.8+/-1.7 mg/dL. None required renal replacement therapy in ARF group. Mean admission durations were 4.4+/-2.8 and 14.0+/-11.5 days. Survival rate was 12.5% in ARF group, which was significantly low compared to 75% in non-ARF group.
CONCLUSION
In spite of high mortality rate in ARF group, ARF by itself was not a direct cause of death. We suggest that the development of ARF is a predicting but not a causative factor of death in the survivors following CPR.

Keyword

Cardiopulmonary resuscitation (CPR); Acute renal failure (ARF); Clinical factors; Predicting factor of death

MeSH Terms

Acute Kidney Injury
Arterial Pressure
Cardiopulmonary Resuscitation*
Cause of Death
Creatine Kinase
Creatinine
Dopamine
Emergencies
Epinephrine
Gyeonggi-do
Heart Arrest
Humans
Korea
Medical Records
Mortality
Prevalence
Renal Replacement Therapy
Resuscitation
Retrospective Studies
Survival Rate
Survivors
Creatine Kinase
Creatinine
Dopamine
Epinephrine