J Korean Acad Conserv Dent.  2003 Sep;28(5):409-418. 10.5395/JKACD.2003.28.5.409.

The effect of substance P on the secretion of interleukin-8 and MCP (Monocyte Chemoattractant Protein)-1 from the Human Dental Pulp Cells

Affiliations
  • 1Department of Conservative Dentistry, College of Dentistry, Kyung Hee University, Korea. consdent94@hanmail.net

Abstract

No abstract available.


MeSH Terms

Dental Pulp*
Humans*
Interleukin-8*
Substance P*
Interleukin-8
Substance P

Figure

  • Fig. 1 Dose response of IL-8 secretion in human pulp cells stimulated with sp.

  • Fig. 2 IL-8 secretion from the pulp cells following SP stimulation.

  • Fig. 3 IL-8 secretion from ECV 304 cells in response to SP stimulation.

  • Fig. 4 ELISA detection of IL-8 from the pulp cells stimulated with SP, CGRP, or SP+CGRP.

  • Fig. 5 ELISA detection of IL-8 from ECV 304 cells stimulated with SP, CGRP, or SP+CGRP.

  • Fig. 6 MCP-1 secretion from the pulp cells in response to SP stimulation.

  • Fig. 7 MCP-1 secretion from ECV304 cells in response to SP stimulation.

  • Fig. 8 IL-8(A) and MCP-1(B) secretion from pulp cells following SP(10-4 M) stimulation in the course of time.

  • Fig. 9 IL-8 secretion from ECV 304 cells following SP(10-5 M) stimulation(A) and MCP-1 secretion from ECV 304 cells following SP(10-4 and 10-5 M) stimulation(B) in the course of time.


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