Korean J Med.  2003 Jan;64(1):114-118.

A case of relapsed renal plasmacytoma after complete remission of multiple myeloma

• Kim SH
• Kim ES
• Hur JW
• Lee JH
• Chang SH
• Kim YS
• Eo WK

Abstract

Extramedullary plasmacytoma is a rare presentation of plasma cell dyscrasia. Most such tumors arise on the upper aerodigestive tract and renal plasmacytoma is very rare. The patient was 44 years old female presented with a 3 month-history of palpable mass in the right flank. There was a past history of complete remission after a chemotherapy for multiple myeloma (6 cycles of VAD chemotherapy) for the two years following the first diagnosis. After surgical resection, histologic and immunofluorescence studies of resected specimens revealed that the renal parenchyma was destroyed by sheets of mature plasma cells producing monoclonal protein (IgG-lambda) and by deposits of amorphous eosinophilic substance stained with anti-lambda antisera. Treatment with chemotherapy of Hyper-CVAD and local irradiation was done. The patient has been disease-free for 3 months after treatment. We report a case of relapsed renal plasmacytoma after complete remission of multiple myeloma.

Keyword

Renal plasmacytoma; Multiple myeloma

MeSH Terms

Adult
Diagnosis
Drug Therapy
Eosinophils
Female
Fluorescent Antibody Technique
Humans
Immune Sera
Multiple Myeloma*
Paraproteinemias
Plasma Cells
Plasmacytoma*
Immune Sera