Korean J Gynecol Oncol Colposc.  2000 Sep;11(3):301-305.

A Case of Delivery of Normal Term Baby after Treatment of Gonadoblastoma with Dysgerminoma and Choriocarcinoma in the Ovary in a Woman with 46XX Karyotype

Abstract

A case of gonadoblastoma with dysgerminoma and choriocarcinoma in the right ovary of a 23-year-old woman is reported. A case of gonadoblastoma without a Y chromosome is very rare. She had a 46XX chromosomes, normal genitalia, no history of menstrual irregularities, thereby differing from the other reproted case. The patient had a normal term pregnancy 2 years after surgery and chemotherapy. It is suggested that gonadoblastoma may occur in functionally and morphologically normal gonads. There have been no signs of recurrence or metastasis for 3 years after the first operation.

Keyword

gonadoblastoma; dysgerminoma; choriocarcinoma; karyotype

MeSH Terms

Choriocarcinoma*
Drug Therapy
Dysgerminoma*
Female
Genitalia
Gonadoblastoma*
Gonads
Humans
Karyotype*
Neoplasm Metastasis
Ovary*
Pregnancy
Recurrence
Y Chromosome
Young Adult
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