Korean J Pediatr Gastroenterol Nutr.
2004 Mar;7(1):78-82.
Treatment of Severe Small Bowel Involvement in Henoch-Schonlein Purpura: Two Cases Report
- Affiliations
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- 1Department of Pediatrics, Ilsan Paik Hospital, College of Medicine, Inje University, Ilsan, Korea. jsmoon@ilsanpaik.ac.kr
- 2Department of Pediatric Surgery, Ilsan Paik Hospital, College of Medicine, Inje University, Ilsan, Korea.
- 3Department of Diagnostic Radiology, Ilsan Paik Hospital, College of Medicine, Inje University, Ilsan, Korea.
- 4Department of Diagnostic Pathology, Ilsan Paik Hospital, College of Medicine, Inje University, Ilsan, Korea.
Abstract
- Henoch-Schonlein purpura (HSP) is a vasculitis of the small vessels in skin, joints, gastrointestinal (GI) tract and kidney. GI symptoms occur in up to 85% of patients and may lead to severe problems such as intussusception, obstruction, and perforation. GI symptoms may not be easily controlled, showing refractoriness to the conventional corticosteroid therapy. Although GI involvements of HSP are acute, and self-limited in most instances, they may cause fatal results in some unusual cases. In such conditions all the possible therapeutic modalities should be considered. We report two cases of severe small bowel involvement of HSP. One case presented with severe abdominal pain showing refractoriness to corticosteroid, but improved with IV immunoglobulin therapy. In the second case, HSP with transmural infarction in the small bowel could be cured with surgical intervention.
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