Korean J Pediatr.
2005 Mar;48(3):342-345.
A Case of Neonatal Lupus Erythematosus Associated with Anti-U1RNP Antibodies
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Chungbuk National University, Cheongju, Korea.mijung0412@chungbuk.ac.kr
- 2Department of Dermatology & Medical Research Institute, College of Medicine, Chungbuk National University, Cheongju, Korea.
Abstract
- Neonatal lupus erythematosus(NLE) is a distinct subset of lupus characterized by cutaneous findings, cardiac conduction defects, hepatic or hematologic abnormalities. These manifestations are associated with the presence of maternal auto-antibodies such as anti-SSA/Ro, anti-SSB/La, and rarely anti- RNP(U1RNP) antibodies. Cases of U1RNP antibody-positive NLE have somewhat atypical cutaneous manifestation without cardiac or systemic abnormalities. We report a case of cutaneous NLE associated with U1RNP antibodies.