Intest Res.  2013 Jul;11(3):155-160. 10.5217/ir.2013.11.3.155.

The Medical Treatments of Intestinal Behcet's Disease: An Update

• Lee HW
• Kim WH
• Cheon JH

• KMID: 1974778
• DOI: http://doi.org/10.5217/ir.2013.11.3.155

Abstract

Behcet's disease (BD) is a systemic immunological disorder characterized by recurrent mucosal ulcerative lesions including oral and genital ulcerations in association with skin and ocular involvements. BD also can involve the gastrointestinal tract. Gastrointestinal involvement of BD is one of the major causes of morbidity and mortality for this disease. However, clinical data are quite limited because of the rarity of intestinal BD. Therefore, the management of intestinal BD is heavily dependent on expert opinions and standardized medical treatments of intestinal BD are yet to be established. In this brief review, the authors summarized the currently available medical treatments such as 5-aminosalicylic acids, corticosteroids, immuno-modulators, and anti-TNF agents. Moreover, we sought to suggest a treatment algorithm for intestinal BD based on the recently published and updated data.

Keyword

Intestinal Behcet's disease; Corticosteroids; Immunomodulators; Anti-tumor necrosis factor antibody; Inflammatory bowel diseases

MeSH Terms

Adrenal Cortex Hormones
Expert Testimony
Gastrointestinal Tract
Immunologic Factors
Inflammatory Bowel Diseases
Mesalamine
Skin
Ulcer
Adrenal Cortex Hormones
Immunologic Factors
Mesalamine