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Impact of Visceral Fat on Survival and Metastasis of Stage III Colorectal Cancer

Park JW, Chang SY, Lim JS, Park SJ, Park JJ, Cheon JH, Kim WH, Kim TI

Background/Aims: Previous studies have investigated the relationship between visceral obesity and the risk of colorectal tumors. Visceral obesity may affect the outcome of colorectal cancer (CRC), including survival and metastasis....
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Can Anti-Tumor Necrosis Factor Agents Be Discontinued in Patients with Inflammatory Bowel Disease?

Park J, Cheon JH

No abstract available
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Improving the care of inflammatory bowel disease (IBD) patients: perspectives and strategies for IBD center management

Park J, Park S, Lee SA, Park SJ, Cheon JH

The incidence and prevalence rates of inf lammatory bowel disease (IBD) have been increasing in East Asian countries over the past few decades. Accordingly, the general understanding and awareness of...
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Succinate-treated macrophages attenuate dextran sodium sulfate colitis in mice

Park IS, Son M, Ma HW, Kim J, Kim DH, Kim SW, Cheon JH

Background/Aims: The safety and effectiveness of adalimumab was demonstrated in a phase 3 trial in Japanese patients with intestinal Behçet’s disease. The aim of this study was to evaluate the...
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The Management of Foreign Body Sensation in the Throat after Stroke by Trigger Point Injection on Posterior Belly of Digastric Muscles

Kim H, Yang HS, Cheon JH, Won KH

Foreign body (FB) sensation in the throat is often a common symptom encountered in clinical practice. FB sensation in throat has numerous causes mainly caused by reflex diseases such as...
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Comparison of Long-term Outcomes of Infliximab versus Adalimumab Treatment in Biologic-Naïve Patients with Ulcerative Colitis

Lee YI, Park Y, Park SJ, Kim TI, Kim WH, Cheon JH

Background/Aims: The tumor necrosis factor-α inhibitors infliximab and adalimumab are standard treatments for moderate to severe ulcerative colitis (UC). However, there has been no headto-head comparison of treatment efficacy and...
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Incidence and Prevalence of Inflammatory Bowel Disease across Asia

Park J, Cheon JH

Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), are chronic inflammatory disorders of the gastrointestinal tract caused by interactions between genetic, environmental, immunological, and microbial factors....
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Prognostic Value of Terminal Ileal Inflammation in Patients with Ulcerative Colitis

Yu J, Park J, Kang EA, Park SJ, Park JJ, Kim TI, Kim WH, Cheon JH

Background/Aims: Few studies have investigated terminal ileal lesions and their prognostic value in patients with ulcerative colitis (UC). We evaluated the clinical significance of these lesions as a prognostic factor...
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Corrigendum: Unmet Psychosocial Needs of Patients Newly Diagnosed with Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea

Moon JR, Lee CK, Hong SN, Im JP, Ye BD, Cha JM, Jung SA, Lee KM, Park DI, Jeen YT, Park YS, Cheon JH, Kim H, Seo B, Kim Y, Kim HJ, he MOSAIK study group of the Korean Association for the Study of Intestinal Diseases (KASID)

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Advances in Management of Intestinal Behçet’s Disease: A Perspective From Gastroenterologists

Cheon JH

Intestinal Behçet’s disease (intestinal BD) is a rare chronic inflammatory disorder of the intestine that is characterized by recurrent intestinal manifestations with other systemic features of BD. Intestinal BD is...
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Impact of early anti-TNF use on clinical outcomes in Crohn’s disease: a nationwide population-based study

Jung YS, Han M, Park S, Cheon JH

Background/Aims: The optimal timing for initiation of anti-tumor necrosis factor (TNF) therapy in Crohn’s disease (CD) is still debated. Little is known about the clinical outcomes of early versus late...
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mTOR Signaling Combined with Cancer Stem Cell Markers as a Survival Predictor in Stage II Colorectal Cancer

Chang JY, Kim JH, Kang J, Park Y, Park SJ, Cheon JH, Kim WH, Kim H, Park JJ, Kim TI

Purpose: Wnt and mammalian target of rapamycin (mTOR) are major molecular signaling pathways associated with the development and progression of tumor, as well as the maintenance and proliferation of cancer...
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Pathogenesis and clinical perspectives of extraintestinal manifestations in inflammatory bowel diseases

Kim JM, Cheon JH

A considerable number of patients with inflammatory bowel disease (IBD) experience extraintestinal manifestations (EIMs), which can present either before or after IBD diagnosis. Unraveling the pathogenic pathways of EIMs in...
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Unmet Psychosocial Needs of Patients with Newly Diagnosed Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea

Moon JR, Lee CK, Hong SN, Im JP, Ye BD, Cha JM, Jung SA, Lee KM, Park DI, Jeen YT, Park YS, Cheon JH, Kim H, Seo B, Kim Y, Kim HJ, the MOSAIK study group of the Korean Association for the Study of Intestinal Diseases (KASID)

Background/Aims: Limited data are available regarding psychosocial distress at the time of diagnosis of ulcerative colitis (UC). We investigated the psychosocial burden and factors related to poor health-related quality of...
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Risk Factors for Postoperative Recurrence in Korean Patients with Crohn’s Disease

Kim SB, Cheon JH, Park JJ, Kim ES, Jeon SW, Jung SA, Park DI, Lee CK, Im JP, Kim YS, Kim HS, Lee J, Eun CS, Lee JM, Jang BI, Seo GS

Background/Aims: A considerable number of patients with Crohn’s disease still need intestinal resection surgery. Postoperative recurrence is an important issue in Crohn’s disease management, including the selection of high-risk patients....
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Similar Clinical Outcomes of Early andLate Anti-TNF Initiation for Ulcerative Colitis:A Nationwide Population-Based Study

Han M, Jung YS, Cheon JH, Park S

Purpose: The optimal timing of anti-tumor necrosis factor (anti-TNF) initiation in patients with ulcerative colitis (UC) remains unclear. Very little is known about the clinical outcomes after the early versus late...
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Differences of Spinal Curvature, Thoracic Mobility, and Respiratory Strength Between Chronic Neck Pain Patients and People Without Cervical Pain

Cheon JH, Lim NN, Lee GS, Won KH, Lee SH, Kang EY, Lee HK, Cho Y

Objective To investigate the differences of spinal curvature, thoracic sagittal mobility, and respiratory strength between patients with chronic neck pain (CNP) and people without cervical pain, and to determine the...
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Quantitative Proteomic Analysis of the Expression of SARS-CoV-2 Receptors in the Gut of Patients with Chronic Enterocolitis

Park J, Jeong D, Chung YW, Kim DH, Cheon JH, Ryu JH

The cellular entry of severe respiratory syndrome coronavirus-2 (SARS-CoV-2) is mediated by interaction with the human angiotensin-converting enzyme 2 (ACE2), a receptor that is expressed on both lung and intestinal...
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Anti-MAdCAM-1 antibody (PF-00547659) for active refractory Crohn’s disease in Japanese and Korean patients: the OPERA study

Saruta M, Park DI, Kim YH, Yang SK, Jang BI, Cheon JH, Im JP, Kanai T, Katsuno T, Ishiguro Y, Nagaoka M, Isogawa N, Li Y, Banerjee A, Ahmad A, Hassan-Zahraee M, Clare R, Gorelick K, Cataldi F, Watanabe M, Hibi T

Background/Aims: PF-00547659 is a monoclonal antibody against human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) that prevents the binding of α4β7+ lymphocytes to MAdCAM-expressing sites in the gastrointestinal tract with high...
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Is fasting beneficial for hospitalized patients with inflammatory bowel diseases?

Park YE, Park Y, Park SJ, Kim TI, Kim WH, Kim JN, Lee NR, Cheon JH

Background/Aims: Patients with inflammatory bowel disease (IBD) are usually hospitalized because of aggravated gastrointestinal symptoms. Many clinicians empirically advise these patients to fast once they are admitted. However, there has...
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