Gut Liver.  2010 Sep;4(3):373-377.

Efficacy and Long-Term Outcome of Endoscopic Treatment of Sporadic Nonampullary Duodenal Adenoma

Affiliations
  • 1Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. yscho@catholic.ac.kr

Abstract

BACKGROUND/AIMS
Endoscopic resection has proven to be a safe and effective alternative to surgery for duodenal adenomas. However, few data are available on the adequacy of resection and long-term outcomes. This study evaluated the efficacy and longterm endoscopic findings in a cohort of Korean patients who underwent endoscopic mucosal resection (EMR) of sporadic duodenal adenomas.
METHODS
Seventeen patients with nonampullary duodenal adenomas without familial polyposis syndrome and who were treated by EMR between January 2001 and December 2007 were evaluated retrospectively. Their management, follow-up, and outcomes were reviewed.
RESULTS
In total, seventeen lesions were removed from EMR in 17 patients (mean age, 59.3 years; 6 women, 11 men). The mean size of the tumors was 15.1 mm (median, 13 mm, range, 8-27 mm). Of these 17 adenomas, 16 adenomas were tubulous and 1 was tubulovillous. The EMR was performed successfully in all 17 patients in a single session. After a median follow-up period of 29 months (range, 13-72 months), all patients remained in remission. One patient had bleeding at the site of the EMR. There were no perforations after the EMR.
CONCLUSIONS
EMR for sporadic duodenal adenomas seemed to be a safe and effective treatment modality.

Keyword

Duodenal neoplasm; Adenoma; Endoscopic mucosal resection; Treatment efficacy

MeSH Terms

Adenoma
Adenomatous Polyposis Coli
Cohort Studies
Duodenal Neoplasms
Female
Follow-Up Studies
Hemorrhage
Humans
Retrospective Studies
Treatment Outcome
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