Tuberc Respir Dis.  2006 Sep;61(3):273-278. 10.4046/trd.2006.61.3.273.

A Case of Primary Endobronchial Leiomyoma

• Lee HK
• Lee JH
• Kim SH
• Kim TH
• Sohn JW
• Yoon HJ
• Shin DH
• Park SS
• Min KW
• Paik SS
• Kang JH

• KMID: 1970267
• DOI: http://doi.org/10.4046/trd.2006.61.3.273

Abstract

Endobronchial leiomyoma is a rare tumor that accounts for less than 2% of pulmonary benign tumors. A 32 year-old woman was admitted with fever, cough and sputum for a month. She had suffered from intermittent cough over three years. The chest X-ray and chest CT(computed tomography) showed a nodular lesion obstructing the proximal portion of the left lower lobar bronchus and atelectasis of the left lower lobe. Flexible Bronchoscopy detected a mass obstructing the distal portion of the left main bronchus and endobronchial biopsy showed benign smooth muscle cells. There was no abnormal finding in the uterine examination. Therefore this case was diagnosed as primary endobronchial leiomyoma. The lobectomy was performed due to intractable pneumonia and secondary parenchymal destruction. Postoperative course was uneventful and she was discharged in good health.

Keyword

Primary leiomyoma; Endobronchial; Lung

MeSH Terms

Adult
Biopsy
Bronchi
Bronchoscopy
Cough
Female
Fever
Humans
Leiomyoma*
Lung
Myocytes, Smooth Muscle
Pneumonia
Pulmonary Atelectasis
Sputum
Thorax

Figure

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  Figure 1 Chest PA shows atelectasis on left lower lobe.

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  Figure 2 Chest CT shows a mass obstructing the left lower lobar bronchus on oblique sagittal and axial reformation views.

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  Figure 3 Bronchoscopy shows a whitish ovoid mass with smooth-surface, which almost obstructs the distal left main bronchus.

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  Figure 4 The resected tumor A. the tumor has a long stalk(upper). The stalk was segmented during operation. B. the stalk was originated from proximal left lower bronchus and has narrow base(white arrow).

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  Figure 5 Microscopy shows a submucosal leiomyoma composed of spindle-shaped smooth muscle cells (H&E, ×100), which are strongly positive to smooth muscle actin (Inset : ABC, ×400).

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