Yeungnam Univ J Med.  1999 Jun;16(1):108-113. 10.12701/yujm.1999.16.1.108.

Clear cell sarcoma: 1 case report

Affiliations
  • 1Department of Pathology, College of Medicine, Yeungnam University, Taegu, Korea.
  • 2Department of Orthopedic Surgery, College of Medicine, Yeungnam University, Taegu, Korea.
  • 3Department of Diagnostic Radiology, College of Medicine, Yeungnam University, Taegu, Korea.

Abstract

Clear cell sarcoma is a rare soft tissue sarcoma that occurs tendons and aponeuroses, usually of the lower extremities in young adult. The exact histogenesis is not definitely established, We experienced a case of 58 year-old female who presented with a 3.2x2.2cm sized mass located in the subcutaneous tissue on the left lower thigh. The mass was well circumscribed and grayish firm. Two small satellite nodules were also seen. Histologically the tumor was composed of round to fusiform cells with clear or pale eosinophilic cytoplasm and separated into compact nests or short fascicles by delicated fibrous septa. The melanin pigments and hemosiderin were seen. Tumor cells showed positive reaction for S-100 protein and HMB-45. The ultrastructural examination showed abundant mitochondria and melanosomes.

Keyword

Clear cell sarcoma; Soft tissue; Melanosome

MeSH Terms

Cytoplasm
Eosinophils
Female
Hemosiderin
Humans
Lower Extremity
Melanins
Melanosomes
Middle Aged
Mitochondria
S100 Proteins
Sarcoma
Sarcoma, Clear Cell*
Subcutaneous Tissue
Tendons
Thigh
Young Adult
Hemosiderin
Melanins
S100 Proteins
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