J Korean Acad Periodontol.  1997 Mar;27(1):111-116. 10.5051/jkape.1997.27.1.111.

Metastatic Lung Carcinoma Involving the Periodontium : Report of a case

• Shin JY
• Han SB
• Hwang KS
• Kye SB

• KMID: 1959418
• DOI: http://doi.org/10.5051/jkape.1997.27.1.111

Abstract

The oral cavity is easily accessible for direct exposure of a malignant disease. 1 percent of the oral malignant tumors are of metastatic origin and approximately 10 percent to 25 percent of the 1 percent fraction originate from the lungs. A case of metastatic lung carcinoma to the gingiva in a 88-year-old male is reported. He complained of pain and swelling between right maxillary 1st premolar and 2nd molar. Although surgical excision of the lesion has been done, the gingival lesion developed as a quickly growing mass and recurred 2 weeks after surgical excision. The gingival mass was histopathologically diagnosed as an undifferentiated carcinoma. Epithelial layer was continuous without ulceration and it seems that the cancer cells are originated from primary tumor. Infiltrated cancer cells were pleomorphic and dyskeratotic. The cells had 2 or more nuclei, not showing squamous or glandular differentiation. Immunohistochemical study revealed the cells originated from the epithelial cells. The prognosis is poor, because prognosis depends on surgical elimination of the primary tumor.

Keyword

Metastasis; Lung cancer; Undifferentiated carcinoma

MeSH Terms

Aged, 80 and over
Bicuspid
Carcinoma
Epithelial Cells
Gingiva
Humans
Lung Neoplasms
Lung*
Male
Molar
Mouth
Neoplasm Metastasis
Periodontium*
Prognosis
Ulcer