J Korean Med Assoc.  2003 May;46(5):454-460. 10.5124/jkma.2003.46.5.454.

Target Controlled Infusion

• Kim DW

• KMID: 1958036
• DOI: http://doi.org/10.5124/jkma.2003.46.5.454

Abstract

Target controlled infusion(TCI) is an infusion system which allows the anesthetist to select the target blood concentration required for a particular effect and then to control the depth of anaesthesia by adjusting the requested target concentration, which includes the instantaneous calculation of the infusion rate necessary to obtain and maintain a given therapeutic blood concentration of drug based on average pharmacokinetic parameters. We can apply this concept of infusion system not only to anesthetics but also to any kinds of intravenous drug infusion including antibiotics in the future.

Keyword

Target controlled infusion; Target blood concentration

MeSH Terms

Anesthetics
Anti-Bacterial Agents
Anesthetics
Anti-Bacterial Agents

Figure

• 

  Figure 1

• 

  Figure 2

• 

  Figure 3

Reference

1. Target controlled infusion. Abstracts in third international symposium on intravenous anesthesia. 1995. Geneva:

2. Target controlled infusion in anesthetic practice. 1996. Zeneca co..

3. Diprifusor TCI. Abstract in symposium. 1996. In : 11th world congress of anesthesiologists;

4. Guidance on the administration of Diprivan (propofol) by target controlled infusion. 1996. Zeneca co..

5. Ho YK. Target controlled infusion. Intrav Anesth. 1998. 2(2):180–188.