J Korean Neurol Assoc.  2004 Jun;22(3):269-271.

Ataxic Variant of Guillain-Barre Syndrome Associated with Anti-GD1b Ig G Antibody

Affiliations
  • 1Department of Neurology, Kangnam General Hospital Public Corporation, Seoul, Korea.
  • 2Department of Neurology, Sungkyunkwan University School of Medicine, Seoul, Korea. bjkim@smc.samsung.co.kr

Abstract

It is known that anti GD1b antibody bind to the cerebellar granular layer or spinocerebellar Ia fiber. We recently encountered a patient of Guillain Barr syndrome (GBS) showing marked cerebellar ataxia and relatively mild quadriparesis but completely intact extraocular eye movement. Markedly high IgG anti GD1b antibody titer was identified from the patient's serum. The nerve conduction study showed reduction of compound muscle action potential without evidence of perpheral nerve demyelination. We report an ataxic variat of GBS associated with anti GD1b IgG antibody.

Keyword

Guillain-Barre syndrome; Cerebellar ataxia; Autoantibody; Anti GD1b

MeSH Terms

Action Potentials
Cerebellar Ataxia
Demyelinating Diseases
Eye Movements
Guillain-Barre Syndrome*
Humans
Immunoglobulin G
Neural Conduction
Quadriplegia
Immunoglobulin G
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