J Korean Ophthalmol Soc.  1992 Sep;33(9):853-860.

Ultrastructural Studies of Retina and Proliferative Membranes in Coats' Disease Complicated by Proliferative Vitreoretinopathy

Affiliations
  • 1Department of Ophthalmology, Keimyung University School of Medicine, Taegu, Korea.
  • 2Department of Pathology, School of Medicine, Kyungpook National University, Taegu, Korea.

Abstract

Proliferative vitreoretinopathy is the most common complication of retinal reattachment surgery. The condition is characteristerized by the proliferation of cells on both surface of retina resulting in membrane formation and traction on retina. The authors studied the ultrastructural features of preretinal, subretinal membrane and peripheral retinal tissue which were removed during vitreous surgery in eye with Coats' disease complicated by proliferative vitreoretinopathy (Grade D-l). In preretinal membrane, fibrocytes, fibroblasts, myofibroblasts, macrophages and collagen fibrils were observed in central retinal area and fibrocyte, collagen fibril and retinal pigment epithelium in periphe ral retinal area. In subretinal membreane, retinal pigment epithelial cells, macrophage-like cells, fibrin, collagen fibrils and amorphorous materials were observed.

Keyword

Coats' disease; Preretinal membrane; Proliferative vitreoretinopathy; Subretin al membrane

MeSH Terms

Collagen
Epithelial Cells
Fibrin
Fibroblasts
Macrophages
Membranes*
Myofibroblasts
Retina*
Retinal Pigment Epithelium
Retinaldehyde
Traction
Vitreoretinopathy, Proliferative*
Collagen
Fibrin
Retinaldehyde
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