J Korean Ophthalmol Soc.  1993 Jun;34(6):491-498.

An Experimental Study of Noncontact Transscleral Diode Laser Cyclophotocoagulation in Rabbits

• Lee HK
• Park US
• Bae NY
• Shyn KH

Abstract

Acute and long-term effects of the noncontact transscleral diode laser cyclophotocoagulation were studied in 6 pigmented rabbits used laser power level was 0.15J, 0.25J, 0.5J and 0.75J. Each eyeballs was enuleated 1.7 and 21 days after cyclophotocoagulation for histopathologic examination. The findings with diode laser were coagulation necrosis of pigmented epitihelium, nonpigmented epitihelium and stroma, congestion of vessel, pigment dispersion and detachment of pigment epithelium. Twenty one days after laser treatment, the light microscopic examination revealed atrophy of nonpigmented epithelium and pigmented epithelium, fibrosls, pigment laden macrophages. These changes were obvious in rabbits treated with a power more than 0.5J. It is suggested that noncontact trasnscleral cyclophotocoagulation with diode laser is useful in lowering intraocular pressure.

Keyword

Artopily; Coagulation necrosis; Cyclophotocoagulation; Diode laser; Uncontrolled glaucoma

MeSH Terms

Atrophy
Epithelium
Estrogens, Conjugated (USP)
Intraocular Pressure
Lasers, Semiconductor*
Macrophages
Necrosis
Rabbits*
Estrogens, Conjugated (USP)