J Korean Surg Soc.  2005 Sep;69(3):273-277.

Ileal Mesenteric Castleman's Disease

• Choi BJ
• Kim KW
• An CH
• Kim JS
• Yoo SJ
• Lim KW

Abstract

Castleman's disease is a rare disorder characterized by tumorous masses that may develop in the lymph node tissue throughout the body. Most common location is mediastinum, but it can also affect retroperitoneum, neck, pelvis, and/or axilla. It may exceptionally affect extranodal sites like striated muscle, thoracic wall, lungs, skull, larynx, and/or vulva. The presentation is varied and diagnosis is difficult. There are two main types of Castleman's disease: hyaline-vascular type and plasma cell type. The hyaline vascular type accounts for approximately 90% of the cases. Most individuals exhibit no symptoms of this form of the disorder or they may develop non-cancerous growths in the lymph nodes. The plasma cell type is often associated with fever, weight loss, skin rash, early destruction of red blood cells, leading to unusually low levels of circulating red blood cells (hemolytic anemia), and/ or abnormally increased amounts of certain immune factors in the blood (hypergammaglobulinemia). We here report a case of Castleman's disease of ileal mesentery in 30-years old female patient. Abdominal mass, 4.7x3.6 cm in size, was completely removed from ileal mesentery without complication, and confirmed histologically mesenteric Castleman's disease of the mixed type.

Keyword

Castleman's disease; Hyaline vascular type; Plasma cell type; Mesentery

MeSH Terms

Adult
Axilla
Diagnosis
Erythrocytes
Exanthema
Female
Fever
Giant Lymph Node Hyperplasia*
Humans
Hyalin
Immunologic Factors
Larynx
Lung
Lymph Nodes
Mediastinum
Mesentery
Muscle, Striated
Neck
Pelvis
Plasma Cells
Skull
Thoracic Wall
Vulva
Weight Loss
Immunologic Factors