Yonsei Med J.  2005 Apr;46(2):289-291. 10.3349/ymj.2005.46.2.289.

Mesenteric Castleman's Disease

Affiliations
  • 1Department of Surgery, Korea University College of Medicine, Seoul, Korea. gsmin@korea.ac.kr
  • 2Department of Pathology, Korea University College of Medicine, Seoul, Korea.

Abstract

We report here a rare case of mesenteric Castleman's disease presenting as a mesenteric mass. A 13-year-old female child was admitted to our hospital complaining of intermittent vague abdominal pain. She had hypochromic anemia, thrombocytosis and an elevated erythrocyte sedimentation rate (ESR). Ultrasonography and computed tomography indicated an intra- abdominal mass might represent a lymphoma or gastrointestinal stromal tumor or leiomyoma, but the definitive preoperative diagnosis couldn't be confirmed. The surgical resection of the mass revealed the mesenteric hyaline vascular- type Castleman's disease.

Keyword

Mesenteric tumor; Castleman's disease

MeSH Terms

Adolescent
Female
Giant Lymph Node
Humans
*Mesentery
Tomography, X-Ray Computed

Figure

  • Fig. 1 Ultrasonography of the patient shows hypoechocity with small focal peripheral vascularity.

  • Fig. 2 CT scan of the patient shows a well-circumscribed intra-abdominal mass of soft tissue density at the small bowel mesentery.

  • Fig. 3 A. Macroscopically, the mass was egg shaped, and it measured 5.0×4.5×4.0 cm in size. B. The cut surface showed a well defined homogenous brownish mass with multifocal whitish foci.

  • Fig. 4 A. On histopathologic examination, lymphoid follicles with centrally located, thick blood vessels and interfollicular nodular hyalinizing fibrosis (hematoxylin and eosin, 100×). B. A lymphoid follicle containing centrally located blood vessels with deposits of hyalin (hematoxylin and eosin, 200×).


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