Korean J Anesthesiol.  2006 Mar;50(3):341-345. 10.4097/kjae.2006.50.3.341.

Anesthetic Management in a Patient with Charcot-Marie-Tooth Disease: A case report

• Kim ES
• Chang HW
• Hwang WJ
• Lee YK

• KMID: 1936739
• DOI: http://doi.org/10.4097/kjae.2006.50.3.341

Abstract

A 35-year old woman was scheduled to undergo a total hystectomy due to uterine myoma. She had been diagnosed with Charcot-Marie-Tooth disease 2 years ago. In addition, she had previously received a Cesarean section under epidural anesthesia 10 years ago and reported a prolonged motor blockade at that time. General anesthesia was induced with propofol 120 mg in a divided dose and the intubating condition was achieved with vecuronium 3 mg. Anesthesia was maintained with 1.5-2.5% enflurane with air and O2. During surgery, the body temperature and end tidal concentration of CO2 were maintained within the normal range. Despite the continuous monitoring of the train-of-four (TOF) response, no more muscle relaxants were required during surgery and the patient recovered without a delay in awakening. In the management of patients with Charcot-Marie-Tooth disease, it is desirable to evaluate the patient carefully, select the appropriate anesthetics and adjust the dosage of the drug according to the patients requirements.

Keyword

Charcot-Marie-Tooth disease; train-of-four (TOF) response; vecuronium

MeSH Terms

Adult
Anesthesia
Anesthesia, Epidural
Anesthesia, General
Anesthetics
Body Temperature
Cesarean Section
Charcot-Marie-Tooth Disease*
Enflurane
Female
Humans
Leiomyoma
Pregnancy
Propofol
Reference Values
Vecuronium Bromide
Anesthetics
Enflurane
Propofol
Vecuronium Bromide