Korean J Anesthesiol.  2000 Feb;38(2):278-282. 10.4097/kjae.2000.38.2.278.

The Effect of Epidural Block on Renal Function in Patients Undergoing Total Abdominal Hysterectomy with General Anesthesia

• Chang MS
• Kim JY
• Kim JH
• Park YC

• KMID: 1936350
• DOI: http://doi.org/10.4097/kjae.2000.38.2.278

Abstract

BACKGROUND: There are many documents about the hemodynamic changes during sympathetic blockade produced by epidural anesthesia, but few reports have addressed the effects of epidural anesthesia on renal blood flow and function. We evaluated the effects of epidural anesthesia on renal function in patients undergoing total abdominal hysterectomy with general anesthesia.
METHODS
Thirty patients were randomized to groups I (n = 15) or II (n = 15). The epidural catheter was inserted via 17 gauge Tuohy needle through the L2-L3 intervertebral space of the patients in both groups, only in group II, the patients received 15 ml of 0.125% bupivacaine. All the patients were anesthetized with enflurane, nitrous oxide and oxygen. We measured mean arterial pressure and urine output, creatinine clearence, Na clearence, fractional excretion of Na and free water clearance during operation and compared the data between the two groups.
RESULTS
Mean arterial pressure was lower in group II than in group I (P < 0.05), but other data were not different significantly between the two groups.
CONCLUSIONS
Renal function was maintained even though epidural anesthesia reduced mean arterial pressure.

Keyword

Anesthetic techniques: epidural; Kidney: function; Surgery: hysterectomy

MeSH Terms

Anesthesia, Epidural
Anesthesia, General*
Arterial Pressure
Bupivacaine
Catheters
Creatinine
Enflurane
Hemodynamics
Humans
Hysterectomy*
Needles
Nitrous Oxide
Oxygen
Renal Circulation
Water
Bupivacaine
Creatinine
Enflurane
Nitrous Oxide
Oxygen
Water