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Evaluation of copper alloys for reducing infection by methicillin resistant Staphylococcus aureus and vancomycin resistant Enterococcus faecium in intensive care unit and in vitro

Choi SI, Chang MS, Kim T, Chung KH, Bae S, Kim SH, Yoon CJ, Kim YK, Woo JH

Background/Aims: Multi-drug resistant pathogens are increasing among healthcare-associated infections. It is well known that copper and copper alloys have antimicrobial activity. We evaluated the activity of copper against bacteria in...
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Standardization of the pathologic diagnosis of appendiceal mucinous neoplasms

Kang DW, Kim Bh, Kim JM, Kim J, Chang HJ, Chang MS, Sohn JH, Cho MY, Jin SY, Chang HK, Han HS, Kim JY, Kim HS, Park DY, Park HY, Lee SJ, Lee W, Lee HS, Kang YN, Choi Y, The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

Although the understanding of appendiceal mucinous neoplasms (AMNs) and their relationship with disseminated peritoneal mucinous disease have advanced, the diagnosis, classification, and treatment of AMNs are still confusing for pathologists...
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Comparing the surgical outcomes of dual-port laparoscopic distal gastrectomy and three-port laparoscopic distal gastrectomy for gastric cancer

Ahn HS, Chang MS, Han DS

Purpose: Many studies have demonstrated that single-incision or reduced-port laparoscopic distal gastrectomy is a feasible method compared to conventional laparoscopic distal gastrectomy. Using rigid-type laparoscope and right-side approach, we could...
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Glia-Like Cells from Human Mesenchymal Stem Cells Protect Neural Stem Cells in an In Vitro Model of Alzheimer's Disease by Reducing NLRP-3 Inflammasome

Hwang M, Song Sh, Chang MS, Koh SH

Background and Purpose: Neural stem cells (NSCs) have the ability to regenerate, proliferate, and differentiate, enabling them to play important roles in the recovery of the damaged nervous system. However,...
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The Korean Repeatable Battery for the Assessment of Neuropsychological Status-Update : Psychiatric and Neurosurgery Patient Sample Validity

Park JO, Koo BH, Kim JY, Bai DS, Chang MS, Kim OL

Objective : This study aimed to validate the Korean version of the Repeatable Battery for the Assessment of Neuropsychological Status Update (K-RBANS). Methods : We performed a retrospective analysis of 283...
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Prognostic Value of the Alcoholic Hepatitis Histologic Score in Korean Patients with Biopsy-Proven Alcoholic Hepatitis

Lee DH, Choi YI, Bae JM, Chang MS, Joo SK, Jung YJ, e Lee KL, Kim BG, Kim W

Background/Aims: The alcoholic hepatitis histologic score (AHHS) is a recently developed clinical model for predicting short-term mortality in Caucasian patients with alcoholic hepatitis (AH). The AHHS has not been extensively...
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Acute Lymphoblastic Leukemia in a Patient Treated with Letrozole and Palbociclib

Park JH, Park H, Kim KH, Kim JS, Choi IS, Roh EY, Kim JE, Chang MS

Palbociclib, in conjunction with endocrine therapy, has been approved for the treatment of patients with advanced breast cancer. The common hematological toxicities associated with palbociclib are leukopenia and neutropenia. However,...
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Standardized Pathology Report for Colorectal Cancer, 2nd Edition

Kim Bh, Kim JM, Kang GH, Chang HJ, Kang DW, Kim JH, Bae JM, Seo AN, Park HS, Kang YK, Lee KH, Cho MY, Do IG, Lee HS, Chang HK, Park DY, Kang HJ, Sohn JH, Chang MS, Jung ES, Jin SY, Yu E, Han HS, Kim YW, The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

The first edition of the ‘Standardized Pathology Report for Colorectal Cancer,’ which was developed by the Gastrointestinal Pathology Study Group (GIP) of the Korean Society of Pathologists, was published 13...
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Pancreatic High-Grade Neuroendocrine Neoplasms in the Korean Population: A Multicenter Study

Kim H, An S, Lee K, Ahn S, Park DY, Kim JH, Kang DW, Kim MJ, Chang MS, Jung ES, Kim JM, Choi YJ, Jin SY, Chang HK, Cho MY, Kang YK, Kang M, Ahn S, Kim YW, Hong SM, on behalf of the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

Purpose The most recent 2017 World Health Organization (WHO) classification of pancreatic neuroendocrine neoplasms (PanNENs) has refined the three-tiered 2010 scheme by separating grade 3 pancreatic neuroendocrine tumors (G3 PanNETs) from...
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Management of Typhoid Fever – Clinical and Historical Perspectives in Korea

Chang MS, Woo JH, Kim S

Typhoid fever, showed a dramatic decrease in its incidence from 56 per 100,000 population just after Korea's independence to
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Olig2-expressing Mesenchymal Stem Cells Enhance Functional Recovery after Contusive Spinal Cord Injury

Park HW, Oh S, Lee KH, Lee BH, Chang MS

BACKGROUND AND OBJECTIVES: Glial scarring and inflammation after spinal cord injury (SCI) interfere with neural regeneration and functional recovery due to the inhibitory microenvironment of the injured spinal cord. Stem...
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FOXO1 Suppression is a Determinant of Acquired Lapatinib-Resistance in HER2-Positive Gastric Cancer Cells Through MET Upregulation

Park J, Choi Y, Ko YS, Kim Y, Pyo JS, Jang BG, Kim MA, Lee JS, Chang MS, Park JW, Lee BL

PURPOSE: Lapatinib is a candidate drug for treatment of trastuzumab-resistant, human epidermal growth factor receptor 2 (HER2)–positive gastric cancer (GC). Unfortunately, lapatinib resistance renders this drug ineffective. The present study...
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A Single Center Analysis of the Positivity of Hepatitis B Antibody after Neonatal Vaccination Program in Korea

Kim YJ, Li P, Hong JM, Ryu KH, Nam E, Chang MS

The antibody to hepatitis B surface antigen (anti-HBs) seropositivity rate after 3 doses of hepatitis B virus (HBV) vaccination during infancy period is known to be higher than 90%. However,...
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Prognostic Influence of BCL2 on Molecular Subtypes of Breast Cancer

Hwang KT, Han W, Kim J, Moon HG, Oh S, Song YS, Kim YA, Chang MS, Noh DY

PURPOSE: We aimed to reveal the prognostic influence of B-cell CLL/lymphoma 2 (BCL2) on molecular subtypes of breast cancer. METHODS: We analyzed 9,468 patients with primary breast cancer. We classified molecular...
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Interleukin-20 targets podocytes and is upregulated in experimental murine diabetic nephropathy

Hsu YH, Li HH, Sung JM, Chen WY, Hou YC, Weng YH, Lai WT, Wu CH, Chang MS

Interleukin (IL)-20, a proinflammatory cytokine of the IL-10 family, is involved in acute and chronic renal failure. The aim of this study was to elucidate the role of IL-20 during...
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Molecular Testing for Gastrointestinal Cancer

Lee HS, Kim WH, Kwak Y, Koh J, Bae JM, Kim KM, Chang MS, Han HS, Kim JM, Kim HW, Chang HK, Choi YH, Park JY, Gu MJ, Lhee MJ, Kim JY, Kim HS, Cho MY, The Gastrointestinal Pathology Study Group of Korean Society of Pathologists, The Molecular Pathology Study Group of Korean Society of Pathologists

With recent advances in molecular diagnostic methods and targeted cancer therapies, several molecular tests have been recommended for gastric cancer (GC) and colorectal cancer (CRC). Microsatellite instability analysis of gastrointestinal...
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Prevention and treatment of healthcare-associated infections

Chang MS, Woo JH

Healthcare-associated infections are infections that develop within a hospital and were not present or incubating upon admission. Almost all healthcare-associated infections become evident 2 days after admission. A patient may...
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Vascular Endothelial Growth Factor Enhances Axonal Outgrowth in Organotypic Spinal Cord Slices via Vascular Endothelial Growth Factor Receptor 1 and 2

Park HW, Jeon HJ, Chang MS

Enhancing adult nerve regeneration is a potential therapeutic strategy for treating spinal cord injury. Vascular endothelial growth factor (VEGF) is a major contributor to angiogenesis, which can reduce the spinal...
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The prevention of pneumococcal infections

Chang MS, Woo JH

No abstract available.
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Degeneration Exists along the Entire Length of the Supraspinatus Tendon in Patients with a Rotator Cuff Tear

Jo CH, Chang MS

BACKGROUND: The purposes of the study were to examine rotator cuff tendon degeneration with respect to harvesting location, to determine a rationale for debridement of the torn end, and thus,...
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