Korean J Anesthesiol.  1979 Mar;12(1):11-15.

The Effect of Premedicants , Diazepam and Atropine Sulfate on Human Thyroxine Levels in Plasma

• Kim DK
• Sohn IJ

Abstract

This study was undertaken to investigate the effect of premedicants, diazepam and atropine sulfate in ten surgical patients by determining human plasma thyroxine levels. Tetrasorb-125 was utilized as a kit which offers a method for quantitative measurement of total circulating serum thyroxine. The plasma thyroxine level before administration of premedicants was 11. 16+/-2. 45ug/100ml and at 60 minutes after administration of premedicants. it was 11. 3+/-2. 73ug/100ml so that clinical significance of the result was absent. The number of male and female patients was 3 and 7, mean age 40. 1+/-9. 82 and average body weight 56. 1+/-4. 01kg. Consequently there was no significant change in human plasma thyroxine during one hour :of premedication.

MeSH Terms

Atropine*
Body Weight
Diazepam*
Female
Humans*
Male
Plasma*
Premedication
Thyroxine*
Atropine
Diazepam
Thyroxine