Korean J Dermatol.  1999 Oct;37(10):1499-1502.

A Case of Varicella in a Full Term Pregnant Woman

Affiliations
  • 1Department of Dermatology, Fatima Hospital, Taegu, Korea.

Abstract

Varicella during pregnancy is a threat to both mother and fetus because of disseminated infection, varicella pneumonia and meningitis etc. And about 10% of babies acquire intrauterine infection, as indicated by the congenital varicella syndrome, neonatal varicella or zoster during infancy. We report a case of varicella in a 30-year-old, 39 weeks and 3 days' gestational age, full-term pregnant woman presented with generalized erythematous papules, vesicles, pustules and umbilicated pustules on the whole body. She was ordered absolute bed rest for delaying the delivery and treated with acyclovir and varicella-zoster immune globulin. However, she delivered a healthy baby which weighed 3,350 gm the next early morning. In our investigation of cord blood after delivery, varicella-zoster IgG and IgM by ELIZA method were negative and varicella-zoster virus DNA by polymerase chain reaction was also negative. The newborn revealed no clinical evidence of skin lesions and anomalies of varicella. So we supposed there was no intrauterine varicella infection.

Keyword

Varicella; Preganacy; Varicella-zoster IgG and IgM; DNA

MeSH Terms

Acyclovir
Adult
Bed Rest
Chickenpox*
DNA
Female
Fetal Blood
Fetus
Gestational Age
Herpes Zoster
Herpesvirus 3, Human
Humans
Immunoglobulin G
Immunoglobulin M
Infant, Newborn
Meningitis
Mothers
Pneumonia
Polymerase Chain Reaction
Pregnancy
Pregnant Women*
Skin
Acyclovir
DNA
Immunoglobulin G
Immunoglobulin M
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