Korean J Gastrointest Endosc.  2004 May;28(5):242-246.

Primary Peripheral T-Cell Lymphoma of the Stomach and Duodenum

• Kim WS
• Lee KM
• Koh BR
• Song YJ
• Choi JH
• Kim JK
• Hahn JH
• Hahm KB
• Kim JH
• Cho SW

Abstract

About 90% of primary gastrointestinal lymphomas originate from the B-cell and less than 10% from the T-cell. In respect of anatomical location, the stomach is the most common site of gastrointestinal lymphomas followed by the ileum, colon, and rectum. However, esophagus and duodenal lymphomas are infrequently involved. Primary T-cell lymphoma of the duodenum is not common and peripheral T-cell lymphoma of the duodenum is very rare. In Korea, there has been no case report of peripheral T-cell lymphoma which simultaneously involved the stomach and duodenum. In this report, we present a case of primary peripheral T-cell lymphoma of the duodenum and stomach. A 63-year-old man was hospitalized complaining of weight loss of 15 kg and dyspepsia for 2 months. Esophagogastroduodenoscopy showed a large annular infiltrative lesion in the descending portion of the duodenum. At the posterior side of the upper body of the stomach, an ill-defined, broad, flat, and infiltrative lesion was also noted. Microscopic examination of the biopsy specimen showed that atypical bizzare lymphocytes infiltrated the mucosa of the duodenum and stomach. The lymphocyte was positive for CD3, CD5 and negative for CD20, CD23, and CD56 by immunohistochemistry. We made a diagnosis of primary peripheral T-cell lymphoma of the stomach and duodenum. We report a case of peripheral T-cell lymphoma of the stomach and duodenum with a review of the literature.

Keyword

Peripheral T-cell lymphoma; Stomach; Duodenum

MeSH Terms

B-Lymphocytes
Biopsy
Colon
Diagnosis
Duodenum*
Dyspepsia
Endoscopy, Digestive System
Esophagus
Humans
Ileum
Immunohistochemistry
Korea
Lymphocytes
Lymphoma
Lymphoma, T-Cell
Lymphoma, T-Cell, Peripheral*
Middle Aged
Mucous Membrane
Rectum
Stomach*
T-Lymphocytes
Weight Loss