Korean J Nucl Med.  2005 Apr;39(2):75-81.

Quantification of Myocardial Perfusion and Function Using SPECT and PET

Affiliations
  • 1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea. jaes@snu.ac.kr

Abstract

Myocardial perfusion and function can be quantified using SPECT and PET. There was controversy over the usefulness of the correction techniques for physical artifacts, such as photon attenuation and scatter, in the quantification of myocardial perfusion using SPECT. However, the cumulated results of many investigations have leaded the consensus on the usefulness of the correction procedures to improve the accuracy and specificity of the myocardial SPECT in the assessment of coronary artery diseases. Although the clinical value of the myocardial perfusion PET has not been proved yet, the absolute myocardial blood flow and perfusion reserve values quantified using myocardial PET are employed in many basic investigations. In this paper, the methods for the quantitative myocardial SPECT and PET will be reviewed.

Keyword

Myocardial perfusion; SPECT; PET; quantification

MeSH Terms

Artifacts
Consensus
Coronary Artery Disease
Perfusion*
Sensitivity and Specificity
Tomography, Emission-Computed, Single-Photon*
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