J Korean Soc Microsurg.  2010 Nov;19(2):81-87.

The Clinical Outcome of Flap Coverage for the Treatment of Malignant Melanoma

• Jeon WJ
• Kang JW
• Kim IH
• Son GS
• Park JW

Abstract

In surgical treatment of the malignant melanoma, radical resection and a sentinel lymph node biopsy are essential procedures to eradicate the tumor and to minimize the risk of local recurrence. For the reconstruction of skin defect after tumor resection, a skin graft has been generally performed procedure. However, if tendon or bone is exposed after tumor resection, simple skin graft is not enough for the coverage of the defect and additional procedure is mandatory. In this study, we reviewed the clinical results of 16 patients, who had been diagnosed with malignant melanoma of the limb and underwent surgical resection and reconstruction of the defect with various methods. The sentinel lymph node dissection was performed in all patients combined with radical excision of the tumor. In 11 cases of positive sentinel lymph nodes, further elective lymph node dissections were performed. The mean tumor invasion depth was 4.54 mm (2~10 mm), and AJCC stage II was most common (9 cases). The pedicled flaps were performed in 10 cases for the reconstruction of defects. All flaps were successfully survived without significant complications until the last follow up. In conclusion, a pedicled flap coverage is very useful reconstruction strategy for the soft tissue defects after radical resection of malignant melanoma.

Keyword

Malignant melanoma; Pedicled flap

MeSH Terms

Extremities
Follow-Up Studies
Humans
Lymph Node Excision
Lymph Nodes
Melanoma
Nitriles
Pyrethrins
Recurrence
Sentinel Lymph Node Biopsy
Skin
Surgical Flaps
Tendons
Transplants
Nitriles
Pyrethrins