Korean J Thorac Cardiovasc Surg.  1999 Feb;32(2):185-188.

1 Case: Pulmonary Giant Cell Carcinoma

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Guro Hospital, Korea University.

Abstract

The pulmonary giant cell carcinoma is classified as a variant of a large cell carcinoma and is diagnosed by the minimum component of 10% huge, pleomorphic and multinucleated giant tumor cell and emperipolesis of the neutrophils into the tumor cells. This tumor is characterized by local recurrences and early metastasis with extremely short patient survival. However, there are some reports that state that the survival time was extended by the operative resection and postoperative adjuvant chemotherapy and radiotherapy. A 46-year old male was admitted with complaint of hemoptysis for 2 months. Through chest X-ray and chest CT, a 5cm sized mass was found in the apical segment of the right upper lobe. During the preoperative evaluation, stenotic lesion in the left anterior descending coronary artery was found and treated by percutaneous transarterial coronary angioplasty. Four weeks later, right upper lobectomy was performed and the mass was proven to be a giant cell carcinoma. The patient received adjuvant chemotherapy and radiotherapy.

Keyword

Carcinoma, bronchogenic; Carcinoma, non-small cell lung; Lung neoplasm

MeSH Terms

Angioplasty
Carcinoma, Bronchogenic
Carcinoma, Giant Cell*
Carcinoma, Large Cell
Carcinoma, Non-Small-Cell Lung
Chemotherapy, Adjuvant
Coronary Vessels
Emperipolesis
Giant Cells*
Hemoptysis
Humans
Lung Neoplasms
Male
Middle Aged
Neoplasm Metastasis
Neutrophils
Radiotherapy
Recurrence
Thorax
Tomography, X-Ray Computed
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