A Study of PTH in Urolithiasis

Kim, Se Joong; Lee, Moo Sang

Abstract

We reviewed 63 urolithiasis patients who were admitted to the Department of Urology, College of Medicine, Yonsei University during the period of 6 months from December, 1983 to May, 1984 to discover hyperparathyroidism in urolithiasis and to evaluate the relationship between PTH and urolithiasis. The following results were obtained. 1. Among 63 urolithiasis patients, there were 47 men and 16 women with a ratio of 2.9: 1 And peak age incidence of urolithiasis occurred in the third and fourth decades (68.3 %). 2. Urinary calculi occurred most commonly in the upper ureter (33.3%) and in decreasing order of frequency kidney and ureter (17.5 %), kidney (16.8 %). 3. In urolithiasis patients, elevated PTH level was found in 5 cases (7.9%) and hypercalciuria was found in 10 cases (15.9 %).And elevated PTH level with hypercalciuria was found in 2 cases(3.2%). 4. In urolithiasis patients, the range of serum calcium, phosphate, protein, albumin and urinaryphosphate, creatinine were within normal limit. And the range of TRP, TRCa were within normal limit, too. 5. Urolithiasis patients with elevated PTH had serum calcium level higher than urolithiasis patients with normal PTH and the difference of the values was statistically significant (P<0.01). But in serum calcium, phosphate, urinary phosphate, TRP and TRCa, the differences of the values between the elevated PTH group and normal PTH group were not statistically significant(p>0.01).