Korean J Urol.  1979 Dec;20(6):562-569.

Effect of Partial Ligation of the Abdominal Aorta on the Glomerular Filtration Rate

• Yoon Y

Abstract

Effect of partial ligation of the abdominal aorta on the glomerular filtration rate (inulin clearance) was observed in 17 male rabbits. Abdominal aorta was ligated to one-half of its original lumen at the level just above branching of the right renal artery under nembutal anesthesia. Seventeen rabbits were observed 30 minutes before the partial ligation, 30 minutes and 90 minutes after the partial ligation. The following results were obtained. 1. Inulin clearance observed 30 minutes before ligation was 1.02+/-0.90 ml/min (Mean+/-S. D.) or 0.52+/-0.46 ml/min/kg in average. 2. Inulin clearance observed 30 minutes after ligation was decreased markedly to 0.46+/-0.58ml/min or 0.23+/-0.29 ml/min/kg in average. 3. Inulin clearance observed 90 minutes after ligation was decreased-slightly to 0.77+/-0.79ml/min or 0.40+/-0.38ml/min/kg in average, suggesting that its findings were occurred by autoregulatory process of the kidney.

Keyword

partial ligation of aorta; GFR

MeSH Terms

Anesthesia
Aorta, Abdominal*
Glomerular Filtration Rate*
Humans
Inulin
Kidney
Ligation*
Male
Pentobarbital
Rabbits
Renal Artery
Inulin
Pentobarbital