J Clin Pathol Qual Control.  1997 Dec;19(2):367-375.

Analysis of Blood Culture Results During 1986-1995

Affiliations
  • 1Department of Clinical Pathology, Yonsei University Wonju College of Medicine, Wonju, Korea.

Abstract

BACKGROUND: Analysis of the distribution of etiologic agents of bacteremia and results of antibiotic susceptibility test is important to improve laboratory systems such as antibiotic susceptibility test, identification, and hospital infection control as well as empirical therapy for the septic patient.
METHODS
Species and antimicrobial susceptibility of isolates from blood cultures obtained from 1986 to 1995 were analysed. Blood specimens were cultured using aerobic and anaerobic media. Organism identifications were based on conventional method or commercial kit systems. Antimicrobial susceptibilities were tested by disk diffusion method.
RESULTS
A total of 76,384 blood specimens were cultured, out of which 12,105 specimens were positive (16.4%). The isolation rate of Enterobacteriaceae decreased from 49.3% in 1986 to 19.3% in 1995. The isolation rate of nonfermentative Gram-negative bacilli (NFB) increased from 9.2% in 1987 to 18.2% in 1988, and ranged from 28% to 34% after 1988. Until 1988, Enterobacteriaceae were the most frequently isolated organisms, followed by Gram-positive cocci, and NFB. This order changed in 1989 due to markedly increased Gram-positive cocci such as coagulase-negative staphylococci (CNS) and alpha-hemolytic streptococci. Salmonella typhi markedly decreased in isolation rate after 1989.
CONCLUSIONS
The most frequently isolated organism in blood culture was Gram-positive cocci. The isolation rate of Enterobacteriaceae did not changed. The isolation rate of anaerobic bacteria was slightly decreased and the isolates of fungi increased during the study period. Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa showed a decreasing trend of susceptible strains to commonly used antimicrobial agents.


MeSH Terms

Anti-Infective Agents
Bacteremia
Bacteria, Anaerobic
Cross Infection
Diffusion
Enterobacteriaceae
Escherichia coli
Fungi
Gram-Positive Cocci
Humans
Pseudomonas aeruginosa
Salmonella typhi
Staphylococcus aureus
Anti-Infective Agents
Full Text Links
  • JCPQC
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr