J Clin Pathol Qual Control.  1997 Dec;19(2):351-360.

Computer-Assisted Delta Check Program on Disk Susceptibility Test

Affiliations
  • 1Department of Clinical Pathology, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 2Medical Information Development, Yonsei University Wonju College of Medicine, Wonju, Korea.

Abstract

BACKGROUND: Quality control techniques of antimicrobial susceptibility test using computer-assisted delta check systems have the advantage of accurate and real time reporting by detection of technical and clerical errors. Therefore promote the performance of delta check system of disk susceptibility tests that were recently developed, we retrospectively analyzed the delta check rate according to organisms and antimicrobial agents using the results of disk susceptibility test obtained from June 1996 to May 1997.
METHODS
This delta check program was designed to detect the discrepancies on patient's disk susceptibility results. We compared present results with previous results of the same specimens that same species were isolated, and the delta check results were displayed on a personal computer's screen for easy verification of the test results. Major difference was defined as susceptible in previous results were interpreted by resistant in present results, and vise versa. Minor difference defined as susceptible/resistant, and intermediate in previous results were interpreted by intermediate, and susceptible/resistant in present results, respectively.
RESULTS
Mean detection rate and major difference by disk susceptibility delta check system were 48.8% and 16.5% in Enterobacteriaceae, and 58.0% and 23.1% in nonfermentative Gram-negative bacilli, respectively. The detection rate of delta check according to organisms were, in order of decreasing frequency, P. aeruginosa, E. coli, A. baumanii, S. marcescens, and K. pneumoniae. Sputum and urine were the most frequently detected specimens in delta check. The delta check rate of aztreonam and third generation cephalosporin with the exception of cefoperazone/sulbactam in Enterobacteriaceae were somewhat higher than other antimicrobials.
CONCLUSIONS
It is concluded that further studies on elucidation about the causative factors of the delta check detection system, and improvement and reformation of the delta check program are needed.


MeSH Terms

Anti-Infective Agents
Aztreonam
Enterobacteriaceae
Humans
Pneumonia
Quality Control
Retrospective Studies
Sputum
Anti-Infective Agents
Aztreonam
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