J Korean Neurosurg Soc.  2003 Oct;34(4):369-371.

Familial Multiple Endocrine Neoplasia, Type I, in Identical Twins

• Kwon WH
• Kim MS
• Jung YT
• Sim JH

Abstract

We report of case of one monozygotic twin sister with pituitary tumor and multiple endocrine neoplasia, type 1.The older sister, 31-year-old woman, had undergone Gamma Knife radiosurgery for prolactin producing pituitary microadenoma. Four years later, pancreatic insulinoma was detected, distal pancreatectomy and splenectomy were done. The younger sister, 31-year-old woman, had been operated for pancreatic insulinoma, 12 years ago. One year ago, hyperparathyroidism and pituitary macroadenoma were detected. Tumor removal was followed by Gamma Knife radiosurgery for residual tumor.

Keyword

Monozygotic twin; Pituitary tumor; Pancreatic insulinoma; Hyperparathyroidism; Familial multiple neoplasm type I

MeSH Terms

Adult
Female
Humans
Hyperparathyroidism
Insulinoma
Multiple Endocrine Neoplasia*
Neoplasm, Residual
Pancreatectomy
Pituitary Neoplasms
Prolactin
Radiosurgery
Siblings
Splenectomy
Twins, Monozygotic*
Prolactin