J Korean Radiol Soc.  1994 Aug;31(2):351-354.

Minocycline Hydrochloride Sclerotherapy of Renal Cysts

• Seong H
• Kweon TB
• Kim HJ
• Jang KJ
• Chun BH
• Shin SK

Abstract

PURPOSE
To report the effectiveness of Minocin sclerotherapy in the treatment of renal cysts.
MATERIALS AND METHODS
We performed minocin sclerotherapy to 19 patients with 21 renal cysts composed of 17 cases of solitary renal cyst and three cases of multiple renal cyst and one case of polycystic kidney comfirmed by ultrasound and CT. After aspiration of cyst fluid, if the amount was less than 50ml, 500mg of minocin was mixed with 3ml of normal saline,if more than 50ml, 1000mg of minocin mixed with 5ml of normal saline were injected, and each case was followed-up over 3 months by ultrasound.
RESULTS
Of all 21 renal cysts, 14 cases were followed-up three months after minocin sclerotherapy. In 12 of 14 cases, the size of the cysts decreased by 10% or collapsed completely. Of the remaining two cases, one collapsed after 6 months while the other recurred after 6months. Three cases were followed up after 20 months and only one of them recurred. 19 of all 21 cases(91%) were cured, and two of 21 cases(9%) were recurred. Pain was the only complaint. and four of 10'cases needed analgesics.
CONCLUSION
Sclerotherapy with minocin has low recurrence-rate and low complication, and relatively early high cure-rate.

MeSH Terms

Analgesics
Cyst Fluid
Humans
Minocycline*
Polycystic Kidney Diseases
Sclerotherapy*
Ultrasonography
Analgesics
Minocycline