J Korean Soc Neonatol.  2000 Nov;7(2):176-180.

A Case of Improved Adrenal Insufficiency with Corticostreoid Treatment, Secondary to Adrenal Hemorrhage

• Oh HS
• Kim SH
• Lee HW
• Seol KH
• Kim GH
• Lee HS

Abstract

The large size and vascularity of the neonatal adrenal glands are vulnerable to traumatic and asphyxial injuries. This condition varies in presentation, which the most common is an abdominal mass alone or mass with jaundice and anemia. Some infants show signs of adrenal insufficiency. Abdomial ultrasonogram is the most valuable diagnostic tool. To result in adrenal insuffiency, hemorrhage must involve both adrenals and at least 90% of the adrenocortical tissue must be destroyed. To affect infant may show signs of hypovolemic shock, electrolyte imbalance and metabolic acidosis. Treatment for adrenal insufficiency must be immediate and vigorous, and consists of intravenous glucose, fluid, and electolyte replacement. And conservative treatment failure is candidate for steroid replacement. We experienced a case of bilateral hemorrhage with adrenal insufficiency, who improved with hydrocortisone.

Keyword

Adrenal insufficiency; Adrenal hemorrhage; Hydrocortisone

MeSH Terms

Acidosis
Adrenal Glands
Adrenal Insufficiency*
Anemia
Glucose
Hemorrhage*
Humans
Hydrocortisone
Infant
Jaundice
Shock
Treatment Failure
Ultrasonography
Glucose
Hydrocortisone