J Korean Soc Pediatr Nephrol.  2007 Apr;11(1):118-125.

A Case of Wegener's Granulomatosis with Multi-organ Involvement in Childhood

• Lee HK
• Cho HY
• Ha IS
• Cheong HI
• Choi Y

Abstract

Wegener's granulomatosis(WG) is a necrotizing granulomatous small vessel vasculitis with a clinical predilection for involvement of the upper airways, lungs and kidneys. The disease usually manifests in adults between 25 and 50 years of age, but it can also rarely occur-in childhood with some features different from those of adults. WG may be easily overlooked in young patients by misinterpretion of the symptoms as caused by an infectious disease of the respiratory tract. Delayed diagnosis and treatment of the disease may cause more rapid progression of the glomerulonephritis to end stage renal disease. We report a boy who was diagnosed with WG with involvement of multiple organs at 13 years of age.

Keyword

Childhood; Wegener's granulomatosis; Multi-organ involvement

MeSH Terms

Adult
Communicable Diseases
Delayed Diagnosis
Glomerulonephritis
Humans
Kidney
Kidney Failure, Chronic
Lung
Male
Respiratory System
Vasculitis
Wegener Granulomatosis*