Korean J Perinatol.  2015 Jun;26(2):109-113. 10.14734/kjp.2015.26.2.109.

Development of Immune Reaction Concept for Perinatology

Affiliations
  • 1Department of Pediatrics, Dongguk University Ilsan Hospital, Dongguk University School of Medicine, Ilsan, Korea. kimhs@dumc.or.kr

Abstract

Most of perinatological phenomenona and diseases are closely related with immune reaction. Most of initial immune responses occur through innate immunity and most causes, such as mechanical damage, hypoxia, and hyperoxia, are self and microorganisms are non-self, all of which are related with immune reaction concept. However, researches on perinatology are mainly focused on specific one or two causes of perinatal diseases, so often there is limitation to understand the basic concepts and phenomenona of the perinatal diseases. Through understanding of immune reaction concept, we can apply immune reaction theory to researches in perinatology and we can understand phenomenona in perinatology through knowledge of immune reaction. Therefore it is essential to understand historical development of immunology and concept of immune reaction for researches and treatment of perinatology.

Keyword

Innate immunity; One-signal theory; Two-signal theory; Danger theory

MeSH Terms

Allergy and Immunology
Anoxia
Hyperoxia
Immunity, Innate
Perinatology*

Reference

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