Hanyang Med Rev.  2007 May;27(2):44-48.

Homograft or Autograft Valve Replacement

• Chang BC
• Lee S

Abstract

Since 1960s, when Ross and Barratt-Boyes introduced homograft replacement of the aortic valve, the valvular replacement using homografts or autografts has been gained increasing acceptance. Aortic or pulmonary valves (with or without associated vascular conduits) transplanted from one individual to another have exceptionally good hemodynamic profiles, a low incidence of thromboembolic complications without chronic anticoagulation, and a low re-infection rate following valve replacement for endocarditis. The homografts were primarily used for complex congenital reconstructions in infants, and children. However, more recently they have been increasingly used in adults requiring aortic valve replacement. Even though there are many advantages, the lack of available homografts, as well as concerns of long-term stenotic problems, may limit their use.

Keyword

Autograft; Homograft; Valve replacement

MeSH Terms

Adult
Allografts*
Aortic Valve
Autografts*
Child
Endocarditis
Hemodynamics
Humans
Incidence
Infant
Pulmonary Valve