Korean J Dermatol.  2006 Oct;44(10):1246-1249.

A Case of Primary Cutaneous Diffuse Large B-cell Lymphoma of the Leg Treated by Total Excision

• Lee JS
• Yun SJ
• Lee JB
• Kim SJ
• Lee SC
• Won YH

Abstract

Primary cutaneous diffuse large B-cell lymphoma of the leg is characterized by a diffuse non-epidermotropic infiltrate predominantly made up of large non-cleaved B-cells, with variable proportions of centroblast- and immunoblast-like cells. We report a case of a 90-year-old female, who presented with a solitary erythematous nodule and ulceration on the lower leg. Physical examination and staging work-up revealed no evidence of systemic involvement. After total excision and a split-thickness skin graft, the skin lesion was almost cleared. Furthermore, no other skin lesion was observed during a 1 year of follow up period.

Keyword

Excision; Primary cutaneous diffuse large B cell lymphoma of the leg

MeSH Terms

Aged, 80 and over
B-Lymphocytes*
Female
Follow-Up Studies
Humans
Leg*
Lymphoma, B-Cell*
Physical Examination
Skin
Transplants
Ulcer