Korean J Dermatol.  1996 Oct;34(5):861-864.

A Case of Granular Cell Tumor

Affiliations
  • 1Department of Dermatology, College of Medicine, Kyunghee University, Seoul, Korea.

Abstract

Granular cell tumors were originally described in 1926 by Abrikossoff as myoblastic myomas. They usually occur as solitary tumors but can be multiple in about 10% of cases. They have a predilection for the head, neck and tongue, but also occur in many other organs. Authors experienced a 37 year-old male patient with a granular cell tumor which exhibited the distinctive histopathologic appearance on light microscopy and electromicroscopy Also, granular cells were S-100 protein, vimentin and CD68 immunoreactive, but desmin and GFAP showed negative immunostaining. This finding suggests a neural origin for grenular cell tumors.

Keyword

Granular cell tumor; Neural origin

MeSH Terms

Adult
Desmin
Granular Cell Tumor*
Head
Humans
Male
Microscopy
Myoblasts
Myoma
Neck
S100 Proteins
Tongue
Vimentin
Desmin
S100 Proteins
Vimentin
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