Korean J Gastrointest Endosc.  1997 Jun;17(3):423-429.

A Case of Mucosa-associated Lymphoid Tissue Lymphoma in Small Intestine

• Kim HW
• Oh ES
• Park SH
• Choi MG
• Cho SH
• Han JY
• Kim JK
• Choi GY
• Chung IS
• Chung KW
• Sun HS
• Kim BS
• Kang CS

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma is the disease of distinctive clinicopathologic entities most of which are different from current lymph-node based lymphoma classification. According to the circulatory properties of the lymphocytes and specific immunoglobulin isotype distribution, MALT is defined as the central lymphoid tissue and is opposed to peripheral somatic lymphoid tissue. It occurs most often in the gastrointestinal mucosa and the bronchial mucosa and may occur in other organs such as salivary gland, thyroid gland, conjunctiva, skin. The most common site of MALT lymphoma is gastrointestinal tract but non-gastrointestinal MALT lymphoma may present. The characteristics of pathology are reactive follicles surrounded by the diffuse infiltration of centrocyte-like (CCL) cells and lymphoepithelial lesion due to the gland invasion of CCL cells. It is a localized disease and has a long survival, Isaacson et al suggested the classification of primary gastrointestinal MALT lymphoma as low grade, high grade, immunoproliferative small intestinal disease (IPSID). The distribution is more often in the stomach than in the intestine. Intestinal MALT lymphomas have less favorable clinicnl courses than the gastric MALT lymphomas. Recurrences may appear in the same organ or in other extranodal sites. We report clinical, pathologic findings, and clinical course in a case of primary small intestinal MALT lymphoma in terminal ileum with literature review.

Keyword

Primary gastrointestinal lymphorma; Mucosa-associated lymphoid tissue (MALT); Centrocyte-like (CCL) cell

MeSH Terms

Classification
Conjunctiva
Gastrointestinal Tract
Ileum
Immunoglobulins
Immunoproliferative Small Intestinal Disease
Intestine, Small*
Intestines
Lymphocytes
Lymphoid Tissue
Lymphoma
Lymphoma, B-Cell, Marginal Zone*
Mucous Membrane
Pathology
Recurrence
Salivary Glands
Skin
Stomach
Thyroid Gland
Immunoglobulins