Korean J Urol.  2014 Apr;55(4):292-294. 10.4111/kju.2014.55.4.292.

Testicular Adrenal Rest Tumor in 11-Beta-Hydroxylase Deficiency Driven Congenital Adrenal Hyperplasia

• Kaynar M
• Sonmez MG
• Unlu Y
• Karatag T
• Tekinarslan E
• Sumer A

• KMID: 1885613
• DOI: http://doi.org/10.4111/kju.2014.55.4.292

Abstract

Testicular adrenal rest tumors (TART) occur often as asymptomatic nodules in corticotropin-dependent lesions aberrant adrenal tissue in congenital adrenal hyperplasia (CAH) patients. The present manuscript is about an unusual case of a 16-year-old CAH patient due to 11beta-hydroxylase deficiency. He underwent testicle biopsy because of testicle tumor suspicion and diagnosed with TART.

Keyword

Adrenal rest tumor; Congenital adrenal hyperplasia due to 11-Beta-hydroxylase deficiency

MeSH Terms

Adolescent
Adrenal Hyperplasia, Congenital*
Adrenal Rest Tumor*
Biopsy
Humans
Testis

Figure

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  FIG. 1 (A) Ultrasonography: image of solid multiple heterogenic hypoechoic nodules with different sizes as indicated by the arrows. (B) Bilateral testicular multinodular mass scrotal magnetic resonance imaging (MRI). (C) Contrast accumulation in bilateral testicular multinodular mass scrotal MRI.

• 

  FIG. 2 (A) Leydig cells with eosinophilic cytoplasm (H&E, ×200). (B) Vimentin immunopositive tumor cells (Vimentin, ×200). (C) MelanA immunopositive tumor cells (MelanA, ×200).

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