Korean J Med.  2014 Mar;86(3):343-348. 10.3904/kjm.2014.86.3.343.

Case of Synchronous Central Neck Node Metastases from Both Primary Thyroid Cancer and from Endometrial Cancer to the Thyroid

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. yjparkmd@snu.sc.kr
  • 2Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 3Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

Abstract

A 54-year-old woman presenting with dizziness was diagnosed with a metastatic brain tumor. Imaging studies to identify the primary cancer revealed endometrial thickening with a left adnexal mass, enlarged bilateral external iliac lymph nodes, and multiple attenuated nodules in both lobes of the thyroid gland with enlarged central neck nodes. After curettage of the uterine endometrium and ultrasonography-guided gun biopsy of the thyroid gland to confirm uterine and thyroid cancers, respectively, total abdominal hysterectomy with bilateral salpingo-oophorectomy and total thyroidectomy with bilateral central neck dissection were performed. Histopathologic examination of the removed tissues demonstrated both endometrial carcinoma metastasis to the thyroid gland and primary thyroid cancer with synchronous central neck node metastasis originating in the endometrium and thyroid. Three of the four right central lymph nodes were positive for metastatic papillary carcinoma; on the other hand, the remaining right central lymph node and one of the two left central lymph nodes were confirmed to be positive for metastatic endometrial carcinoma.

Keyword

Papillary thyroid cancer; Endometrial neoplasm; Lymph nodes; Lymphatic metastasis

MeSH Terms

Biopsy
Brain Neoplasms
Carcinoma, Papillary
Curettage
Dizziness
Endometrial Neoplasms*
Endometrium
Female
Hand
Humans
Hysterectomy
Lymph Nodes
Lymphatic Metastasis
Middle Aged
Neck Dissection
Neck*
Neoplasm Metastasis*
Thyroid Gland*
Thyroid Neoplasms*
Thyroidectomy
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