Korean J Med.  2014 Jan;86(1):106-109. 10.3904/kjm.2014.86.1.106.

Lung Abscess During the Treatment of Relapsed Churg-Strauss Syndrome

• Lee SO
• Choi K
• Kim JH
• Kim HJ
• Jang EY
• Lee BJ
• Choi DC

• KMID: 1867327
• DOI: http://doi.org/10.3904/kjm.2014.86.1.106

Abstract

Churg-Strauss syndrome (CSS) is a rare disease characterized by asthma, peripheral eosinophilia and vasculitis. A quarter of CSS patients with clinical remission have experienced a relapse. We report here a case of lung abscess in a patient with relapsed CSS. A 46-year-old man who achieved clinical remission of CSS was confirmed for relapse by the presence of peripheral eosinophillia, pulmonary lesions and perivascular infiltrate of eosinophils in colon pathology. After administration of systemic glucocorticoid and one cycle of cyclophosphamide pulse therapy, he complained of dyspnea, sputum and chest pain. There were necrotic masses containing internal air-fluid levels in the right upper and the left lower lobes of the lung on chest radiography. Percutaneous needle aspiration culture specimens revealed the presence of K. pneumoniae. The patient was successfully treated with a 5-week course of antibiotics.

Keyword

Churg-Strauss syndrome; Lung abscess

MeSH Terms

Anti-Bacterial Agents
Asthma
Chest Pain
Churg-Strauss Syndrome*
Colon
Cyclophosphamide
Dyspnea
Eosinophilia
Eosinophils
Humans
Lung Abscess*
Lung*
Middle Aged
Needles
Pathology
Pneumonia
Radiography
Rare Diseases
Recurrence
Sputum
Thorax
Vasculitis
Anti-Bacterial Agents
Cyclophosphamide