Korean J Gastroenterol.  2001 Jul;38(1):37-41.

Clinical Characteristics of 19 Cases of Biopsy - proven Eosinophilic Liver Abscess: Single Center Experience

• Jang JK
• Paik SW
• Choi MS
• Lee JH
• Koh KC
• Chae GS
• Kim CS
• Rhee PL
• Kim JJ
• Rhee JC
• Choi KW
• choi DC

Abstract

BACKGROUND/AIMS: Eosinophilic liver abscess is a disease with eosinophilic infiltration and microabscess formation in the liver. Little has been known about the clinical features of patients with eosinophilic liver abscess.
METHODS
The clinical characteristics of 19 patients with biopsy-proven eosinophilic liver abscess were evaluated. The median age of the patients was 52 years (range, 29-69). Their medical records were reviewed to obtain the information about peripheral blood eosinophil count, total serum IgE level, study for parasites, CT findings, clinical course and history of allergy, drugs and foods.
RESULTS
Peripheral eosinophilia was observed in all the patients. Total serum IgE level were elevated in most cases. Stool examination for helminth was positive in one patient and ELISA for antibody to parasite was positive in 7 patients. CT showed multinodular or diffuse mass with low attenuation in all the cases. Sixteen had history of frequent intake of raw fish and uncooked wild animal. Underlying liver disease was found in only one patient. Seven (87.5%) of 8 patients treated with steroid or praziquantel and 6 (60%) of 10 non-treated patients improved.
CONCLUSIONS
Eosinophilic liver abscess should be considered in patients with low attenuation liver mass, a history of intaking raw fish or uncooked wild animal, peripheral eosinophilia, and no underlying liver disease.

Keyword

Ulcerative colitis; Cyclooxygenase-2

MeSH Terms

Animals
Animals, Wild
Biopsy*
Colitis, Ulcerative
Cyclooxygenase 2
Drug Hypersensitivity
Enzyme-Linked Immunosorbent Assay
Eosinophilia
Eosinophils*
Helminths
Humans
Immunoglobulin E
Liver Abscess*
Liver Diseases
Liver*
Medical Records
Parasites
Praziquantel
Cyclooxygenase 2
Immunoglobulin E
Praziquantel