Korean J Dermatol.  2000 Mar;38(3):399-403.

A Case of Squamous Cell Carcinoma Arising in the Lesion of Chronic Discoid Lupus Erythematosus

• Oh KS
• Song MH
• Lee SY
• Lee JS
• Whang KU

Abstract

Squamous cell carcinoma(SCC) is a recognized late complication of chronic discoid lupus erythematosus(CDLE). There are many case reports of SCC in white patients with chronic DLE. However, it is uncommon in blacks and Asians. The etiology of squamous cell carcinoma is multifactorial. The predisposing factors for the development of SCC in these patients include actinic keratosis, Bowen's disease, burn scars, arsenic keratosis, and chronic discoid lupus erythematosus. Of these causes, SCC developing in the lesions of CDLE is very rare. We report a patient who has been evaluated for ten years with a diagnosis of discoid lupus erythematosus and has squamous cell carcinoma.

Keyword

Squamous cell carcinoma; Discoid lupus erythematosus

MeSH Terms

African Continental Ancestry Group
Arsenic
Asian Continental Ancestry Group
Bowen's Disease
Burns
Carcinoma, Squamous Cell*
Causality
Cicatrix
Diagnosis
Humans
Keratosis
Keratosis, Actinic
Lupus Erythematosus, Discoid*
Arsenic