Radiat Oncol J.
2013 Mar;31(1):48-54. 10.3857/roj.2013.31.1.48.
Cases report of unicentric Castleman's disease: revisit of radiotherapy role
- Affiliations
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- 1Department of Radiation Oncology, Ajou University School of Medicine, Suwon, Korea.
- 2Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. lsw@amc.seoul.kr
- 3Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- 4Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- 5Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- KMID: 1842032
- DOI: http://doi.org/10.3857/roj.2013.31.1.48
Abstract
- Castleman's disease or angiofollicular lymph node hyperplasia is a rare lymphoproliferative disorder. Complete surgical resection was recommended in unicentric Castleman's disease. Radiotherapy was considered alternative therapeutic option. However, there have been consistent favorable responses to radiotherapy. We also experienced two cases of uncentric Castleman's disease salvaged successfully with radiotherapy. This paper described these cases and reviewed the literature about Castleman's disease treated with radiotherapy. Reviewed cases showed that radiotherapy is a successful treatment option in unicentric Castleman's disease. Furthermore, our report confirms the radiotherapy role in uncentric Castleman's disease.
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