1. Uematsu S, Udvarhelyi GB, Benson DW, Siebens AA. Percutaneous radiofrequency rhizotomy. Surg Neurol. 1974; 2:319–25.
2. Shealy CN. Percutaneous radiofrequency denervation of spinal facets. Treatment for chronic back pain and sciatica. J Neurosurg. 1975; 43:448–51.
3. Moon SH, Lee S, Kim KH, Rho JH, Kim JH, Jung WS. Effect of ultrasound-guided lumbar medial branch block in chronic low back pain. J of Korean Orthopaedic Research Society. 2012; 15:54–61.
4. Cohen SP, Strassels SA, Kurihara C, et al. Randomized study assessing the accuracy of cervical facet joint nerve (medial branch) blocks using different injectate volumes. Anesthesiology. 2010; 112:144–52.
Article
5. Thorburn J, Moir DD. Bupivacaine toxicity in association with extradural analgesia for caesarean section. Br J Anaesth. 1984; 56:551–3.
Article
6. Gould DB, Aldrete JA. Bupivacaine cardiotoxicity in a patient with renal failure. Acta Anaesthesiol Scand. 1983; 27:18–21.
7. Buffington CW. The magnitude and duration of direct myocardial depression following intracoronary local anesthetics: a comparison of lidocaine and bupivacaine. Anesthesiology. 1989; 70:280–7.
8. Strichartz GR, Sanchez V, Arthur GR, Chafetz R, Martin D. Fundamental properties of local anesthetics. II. Mea-sured octanol: buffer partition coefficients and pKa values of clinically used drugs. Anesth Analg. 1990; 71:158–70.
9. Wildsmith JA, Brown DT, Paul D, Johnson S. Structure-activity relationships in differential nerve block at high and low frequency stimulation. Br J Anaesth. 1989; 63:444–52.
Article
10. Scholz A. Mechanisms of (local) anaesthetics on voltage-gated sodium and other ion channels. Br J Anaesth. 2002; 89:52–61.
Article
11. Ibusuki S, Katsuki H, Takasaki M. The effects of extracellular pH with and without bicarbonate on intracel-lular procaine concentrations and anesthetic effects in crayfish giant axons. Anesthesiology. 1998; 88:1549–57.
Article
12. Cohen SP, Raja SN. Pathogenesis, diagnosis, and treatment of lumbar zygapophysial (facet) joint pain. Anesthesiology. 2007; 106:591–614.
Article
13. Manchikanti L, Singh V, Falco FJ, et al. Evaluation of lumbar facet joint nerve blocks in managing chronic low back pain: a randomized, double-blind, controlled trial with a 2-year followup. Int J Med Sci. 2010; 7:124–35.
Article
14. Alhelail M, Al-Salamah M, Al-Mulhim M, Al-Ha-mid S. Comparison of bupivaaine and lidocaine with epinephrine for digital nerve blocks. Emerg Med J. 2009; 26:347–50.
15. Chu CR, Izzo NJ, Papas NE, Fu FH. In vitro exposure to 0.5% bupivacaine is cytotoxic to bovine articular chon-drocytes. Arthroscopy. 2006; 22:693–9.
Article
16. Gomoll AH, Yanke AB, Kang RW, et al. Longterm effects of bupivacaine on cartilage in a rabbit shoulder model. Am J Sports Med. 2009; 37:72–7.
Article
17. Lehner C, Gehwolf R, Hirzinger C, et al. Bupivacaine induces short-term alterations and impairment in rat tendons. Am J Sports Med. 2013; 41:1411–8.
Article
18. Gomoll AH, Kang RW, Williams JM, Bach BR, Cole BJ. Chondrolysis after continuous intra-articular bupivacaine infusion: an experimental model investigating chondrotoxicity in the rabbit shoulder. Arthroscopy. 2006; 22:813–9.
Article
19. Padera R, Bellas E, Tse JY, Hao D, Kohane DS. Local myotoxicity from sustained release of bupivacaine from microparticles. Anesthesiology. 2008; 108:921–8.
Article