J Korean Soc Neonatol.  2001 May;8(1):166-170.

A Case of Koebner Variant of Epidermolysis Bullosa Simplex

• Lim SJ
• Jung SP
• Lim IS
• Lee DK
• Yoo BH

Abstract

Epidermolysis bullosa simplex (EBS), characterized by a cleavage plane through basal keratinocytes, is caused by a mutation of the genes encoding keratin 5 and 14. It is often regarded as the least severe form of Epidermolysis bullosa. In 1886, Koebner described the seasonal blisterings predominantly on the palms and soles but occurring on the other sites of friction with clothes as well. His name is often used to describe EBS with the generalized blisterings. We have experienced a case of Koebner variant of EBS in a two-day old male neonate whose father had the same EBS. Hereby, we report his clinical, histopathological findings with a brief review of the literature.

Keyword

Epidermolysis bullosa simplex; Koebner variant; Neonate

MeSH Terms

Blister
Epidermolysis Bullosa Simplex*
Epidermolysis Bullosa*
Fathers
Friction
Humans
Infant, Newborn
Keratin-5
Keratinocytes
Male
Seasons
Keratin-5