J Korean Soc Biol Psychiatry.  1998 Jun;5(1):129-133.

A Case on Risperidone-Induced Tardive Dyskinesia

• Kim HS
• Kim HS
• Min BK

Abstract

OBJECTIVE
Base on clinical practice, the authors report a case of tardive dyskinesia arising during the course of treatment with resperidal.
METHODS
This article was review and analysis of a case on risperidone-induced tardive dyskinea.
RESULTS
Mrs K, a 51-year-old women with a 1-year history of schizophrenic disorder, gradually developed tardive dyskinetic movement of the mouth, lip, and tongue over a 4 month period(From July 1996 to June 1997) while taking risperidone. Initially she was treated with haloperidol and alprazolam. However, the haloperidol was subsequently discontinued because of EPS developed. From 11th March 1997, she was observed to have a severe form of tardive dyskinesia involving her tongue, lip, and mouth. After risperidone was withdrawn at 9th May 1997, her tardive dyskinetic movement was disappeared.
CONCLUSIONS
This is, to our knowledge, the first report of the onset of tardive dyskinesia in a patient taking risperidone. However, additional controlled studies of specific questions are needed ; e.g., the dose-response curves for produce tardive dyskinesia and the mechanism of producing risperidone-induced tardive dyskinea and so on.

MeSH Terms

Alprazolam
Female
Haloperidol
Humans
Lip
Middle Aged
Mouth
Movement Disorders*
Risperidone
Schizophrenia
Tongue
Alprazolam
Haloperidol
Risperidone